FcγRIIA activation induces the production of pro-inflammatory cytokines, including IFN and TNFα, which are active in the promotion of inflammation, systemic lupus erythematosus (SLE), Kawasaki disease (KD), Grave's disease, and Rheumatoid Arthritis (RA) (35, 165–167). Here, IFNA1 is linked to rheumatoid arthritis.