While we observed the relative proportions of SAT CD4+ and CD8+ TCM, TEM, and TEMRA cells to be similar regardless of metabolic status in PLWH (Figure 3), expression of CD69 on CD4+ T cells rose with progressive glucose intolerance in a step-wise progression from non-diabetic, to pre-diabetic, to diabetic. The gene discussed is CD4; the disease is Glucose intolerance.