FASLG and autoimmune polyendocrinopathy: According to our review, non organ-specific aPL autoantibodies, particularly aCL and aβ2GPI, that could account for APS patients with MS-like syndrome, occur within a range between 2% and 88% according to the different studies, with predominant IgM over IgG isotype, both in serum and CSF (Table 1).