The first and the most common detected autoantibodies in MS recognize the complexes of membrane proteins assembled to myelin lipids, like the transmembrane proteolipid protein (PLP), the extrinsic myelin basic protein (MBP), the myelin oligodendrocyte glycoprotein (MOG) and the myelin associated glycoprotein (MAG; Kanter et al., 2006; Podbielska and Hogan, 2009). The gene discussed is MOG; the disease is myeloid sarcoma.