ZBTB33 and chronic myelogenous leukemia, BCR-ABL1 positive: In humans, the Wnt11 promoter contains a conserved Kaiso-binding site (at -775), and experimental laboratory results have indicated cooperation between β-catenin/TCF and Kaiso/p120ctn in the negative regulation of Wnt11 transcription in chronic myeloid leukemia (CML) [20].