In primary human breast tumors, the most common ITGB1 isoform 1 A was positively correlated to Suppressor-SFs such as DDX3X and DHX9 (Fig. 4D) while being negatively correlated to Enhancer-SFs such as CCDC12 and FAM50A (Fig. 4E). The gene discussed is DDX3X; the disease is breast neoplasm.