UCA1 and neoplasm: Notably, we observed UCA1 overexpression was significantly associated with up-regulation of CXCR4 in PCa (r = 0.5033, P=0.0009), highlighting the clinical significance of these results, as these suggest that the up-regulation of UCA1 abrogates the tumor suppressive effect of miR-204 on its downstream target CXCR4 in PCa.