Furthermore, the neutrophil chemoattractant CXCL5, the glucose transporter that fuels glycolysis, Slc5A9, the rate-limiting enzyme in the cholesterol biogenesis pathway, Hmgcr (3-hydroxy-3-methylglutaryl–coenzyme A reductase), and the basolateral cholesterol efflux transporter Abca1 were also found among top 100 proteins with significantly increased abundance during infection. This evidence concerns the gene HMGCR and infection.