To examine whether Dnmt1 up‐regulation in SBMA results in increased DNA methylation in the CpG island region of the promoter, which controls the expression of downstream genes, we performed DNA methylation array analysis using human neuroblastoma SH‐SY5Y cells stably expressing human AR containing 24 or 97 glutamine residues (SH24Q, SH97Q), treated with DHT. Here, DNMT1 is linked to neuroblastoma.