ZCCHC13 and hepatocellular carcinoma: The mean absorbance value (1.68 ± 0.01) recorded for patients with HCC (n = 61) was significantly higher than the mean value (0.95 ± 0.05) for healthy controls (n = 38) (p < 0.0001) (Fig. 3c), indicating that ZCCHC13 protein was strongly recognized by sera from patients with HCC compared with healthy controls.