CCL2 and infectious otitis media: The pro-inflammatory chemokine CCL2 was significantly increased in the cortex of TGFβR2wt/wt AOM-treated mice compared to vehicle-treated TGFβR2wt/wt mice, with TGFβR2ΔNeu AOM-treated mice having no significant change compared to vehicle-treated TGFβR2wt/wt mice (Fig. 5b).