CX3CL1 and infectious otitis media: The anti-inflammatory chemokine CX3CL1 was significantly decreased in the cortex of TGFβR2wt/wt AOM-treated mice, but not in TGFβR2ΔNeu AOM-treated mice, when both groups were compared to vehicle-treated TGFβR2wt/wt mice, (Fig. 5c).