TDEs containing MALAT1 (metastasis-associated lung adenocarcinoma transcript 1) which is associated with angiogenesis and metastasis in epithelial ovarian cancer (EOC), induce pro-angiogenesis gene expression in human umbilical vein endothelial cells (HUVECs) [78] (Fig. 2). The gene discussed is MALAT1; the disease is ovarian carcinoma.