In our bronchial epithelium analysis of airway disease, the genes CLDN10 (claudin 10), TMEM2 (CEMIP2 - cell migration inducing hyaluronidase 2) and ALDH1A3 (aldehyde dehydrogenase 1 family member A3) were significant across the three airway-disease variables. The gene discussed is ALDH1A3; the disease is glycogen storage disease VI.