Interestingly, a prospective, randomized controlled study is currently ongoing in Japan for patients with NSCLC and IPF to evaluate the efficacy and safety of chemotherapy with or without nintedanib, which inhibits receptor tyrosine kinase signaling by VEGF, platelet-derived growth factor, and fibroblast growth factors [28]. Here, NTRK1 is linked to idiopathic interstitial pneumonia.