It is known that cPLA2 and PLB activity promotes formation of arachidonic acid from cellular membranes, which in turn activates cellular cyclooxygenase and lipoxygenase enzymes to secrete inflammation mediators such leukotrienes, thromboxanes, and prostaglandins, and cellular downstream pathways by PKC activation to control infections [17,37]. The gene discussed is PLB1; the disease is infection.