However, patients in the Nishida et al. (2013) study were not taking any cholinergic medications whereas the large majority of our patients were on cholinesterase inhibitors, which have been shown to alter resting state EEG characteristics in Alzheimer’s disease (Babiloni et al., 2013) and might thus be an explanation for the different results. This evidence concerns the gene BCHE and early-onset autosomal dominant Alzheimer disease.