Hematopoietically expressed homeobox (HHEX), an overlapping gene between T2DM and CML, was significantly associated with T2DM and was found to inhibit Vascular endothelial growth factor (VEGF) signaling and promote cell survival in CML according to published literatures.18 The gene discussed is HHEX; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.