APP and cancer: Analyses of the biological network by cytoscape revealed protein outliers that have been reported in radiotherapy resistance in cancer and survival, as well as proliferation and epigenetic regulation, such as EGFR (Lee et al., 2011), MOV10 (El Messaoudi‐Aubert et al., 2010), ELAVL1 (Mehta et al., 2016), SIRT7 (Chen et al., 2017; Tang et al., 2017), APP (Lim et al., 2014) and EWSR1 (Suzuki et al., 2012).