The level of IL-16 in the plasma of ITP patients with active disease was significantly higher than that of healthy controls (mean ± SEM: 187.7 ± 24.06 (n = 52) vs. 57.14 ± 4.344 (n = 26), P < 0.0001, Mann-Whitney U-test) (Figure 1B). This evidence concerns the gene IL16 and autoimmune thrombocytopenic purpura.