CASP3 and autoimmune thrombocytopenic purpura: Consistent with the plasma IL-16 level, the relative amount of mRNA of pro-IL-16 and caspase-3 of PBMCs in patients with active ITP was 0.09917 ± 0.03048 (n = 33, P < 0.0001) and 0.07495 ± 0.03843 (n = 33, P < 0.0001) relative to that in healthy controls (0.02230 ± 0.006397 and 0.009746 ± 0.001849, respectively; n = 19).