IL16 and autoimmune thrombocytopenic purpura: The concentration of IL-16 in the bone marrow supernatants of ITP patients with active disease was significantly higher compared with that of the healthy controls (mean ± SEM: 1686 ± 195.6 (n = 19) vs. 287.1 ± 62.27 (n = 9), P = 0.0002, Mann-Whitney U-test) (Figure 1A).