NAF1 and central nervous system cancer: Expectedly, our data presented that NAF1 ectopic expression in glioma cells dramatically accelerated 18S rRNA processing and 40S ribosome synthesis through increasing the levels of the scissor U17 H/ACA snoRNA, while NAF1 depletion in glioma cells obviously impaired the removal of 5′ETS of pre-rRNA, the maturation of 18S rRNA and the formation of 40S ribosomal subunit.