Hyperglycaemia is common in patients receiving nutritional support in non-critical care, occurring in up to half of those receiving parenteral nutrition and in a third of those receiving enteral nutrition.2, 3 The carbohydrate content of nutritional support can exacerbate other causes of hyperglycaemia in hospital inpatients, such as metabolic responses to acute illness and medications that alter insulin sensitivity (eg, glucocorticoids). This evidence concerns the gene INS and Hyperglycemia.