Although the VEGFA copy number was measured only in part of the HCC cohort (n = 41) and in healthy controls, it was significantly higher in HCC patients than in healthy controls (median, 2.50 [range, 2.06–3.50] vs. 2.17 [range, 2.02–2.44], respectively; P < 0.0001) (Fig. 2b). This evidence concerns the gene VEGFA and hepatocellular carcinoma.