In this respect, the most common somatic mutations of Kirsten Rat Sarcoma Viral Oncogene Homolog KRAS and BRAF oncogenes are known to play an important role in the advance and progression of both colorectal cancer (CRC) and melanoma [1,2,4,5,6,7,8,9,10,11]. The gene discussed is KRAS; the disease is colorectal carcinoma.