The second metallopeptidase purified and characterized from TsV was an Angiotensin-Converting Enzyme-like (ACE) peptidase [21], and its ability to release angiotensin II from angiotensin I might contribute to hypertension, which is a symptom that is commonly described on patients envenomed by the T. serrulatus scorpion. This evidence concerns the gene AGT and Hypertension.