We confirmed significant negative association of PON1 paraoxonase activity with diabetes (p = 0.024, Table 5) and positive family history (p = 0.027, Table 6) and these associations were independent of sex, levels of HDL-C, LDL-C triglycerides, previous infarction and genotype, which were introduced to the regression models as covariates. The gene discussed is PON1; the disease is infarction.