In another study, even a reduction of MMP-9 concentration and activity has been reported in the plasma of LMWH-treated patients with abdominal aortic aneurysm [57], an effect which might be connected to the LMWH-dependent downregulation of IL-8 as shown in enoxaparin-treated epithelial cells [48]. Here, CXCL8 is linked to abdominal aortic aneurysm.