Nevertheless, the transient expression (lamin A only, lamin C only or both lamins A and C (to maintain the 1:1 stoichiometry of lamin A/C)) of other variants for DCM (p.D192G, p.N195K) or EDMD (p.R386K) in Cos7 and H9C2 (rat cardiomyoblast cell line) cells resulted in large and multiple lamin aggregates, which also fail to connect to the nuclear envelope unlike cells expressing WT or an FPLD (p. R482W) mutant lamin A/C [54]. Here, LMNA is linked to familial dilated cardiomyopathy.