The zebrafish lmna is an orthologue of human LMNA. The zebrafish is an established model of cardiac diseases owing to its cardiac system’s relative comparability to its mammalian counterpart, its transparency during early development, which allows for organ observation, its high fecundity and its ability to tolerate severe cardiac dysfunction that would be lethal at the foetal level in mammals [99,100]. This evidence concerns the gene LMNA and heart disorder.