Antibodies against the histidine-rich antigen of the malaria parasite Plasmodium [44] or the glutathione-S-transferase from Schistosoma japonicum could lead to undesirable cross-reactions to recombinant proteins tagged with His6 or glutathione-S-transferase, especially as malaria and schistosomiasis occur frequently in dengue endemic regions. Here, HPGDS is linked to malaria.