Moreover, obestatin has been shown to inhibit the development of acute pancreatitis evoked by cerulein [302] or pancreatic ischemia followed by reperfusion [303], as well as exhibits a therapeutic effect in these models of acute pancreatitis [304,305], leading to a reduction in the severity of acute pancreatitis and the acceleration of pancreatic recovery [302,303]. Here, GHRL is linked to acute pancreatitis.