MCT1 was widely distributed in various tissues and organs throughout the body, including normal tissues (e.g., skeletal muscles, adipose tissue, and brain) and pathological tissues (e.g., cancer tissue), and played an important role in many metabolic pathways, such as glycometabolism, lipogenesis, gluconeogenesis, and oxidative phosphorylate metabolic pathway. This evidence concerns the gene SLC16A1 and cancer.