For example, Ho et al. [39] concluded that the PLA2 activity of Prdx6 is necessary for lung cancer cell invasion, by showing that Prdx6 carrying the S32A mutation was much less stimulatory of the invasiveness of transfected A549 cells than wild-type Prdx6 and concluded that this was due to the lack of PLA2 activity. This evidence concerns the gene PRDX6 and lung carcinoma.