Whereas PTX‐3 has been primarily studied for its antifungal role, recent findings have identified it as a diagnostic marker and protective protein during sepsis.46, 47 Immunosuppressive treatment further increases risks of severe sepsis consequences,48, 49, 50, 51 which is particularly intriguing given the pivotal role of monocytes in sepsis,45, 52 and the results presented here. The gene discussed is PTX3; the disease is Sepsis.