Among 80 individuals with vascular dementia, greater IL6 concentrations were independently associated with lower BI scores in a cross-sectional analysis.[22] Among 1727 individuals >70 years of age in the Duke Established Populations for Epidemiologic Studies of the Elderly study,[23] higher IL6 concentrations were associated with disability and self-rated health, and IL6 concentrations were positively associated with cancer, heart attack, and hypertension. Here, IL6 is linked to vascular dementia.