Lipoprotein-associated phospholipase-A2 (LpPLA2) is secreted by immune cells in arterial walls and is involved in inflammatory processes in atherosclerotic plaque.[2] Elevated LpPLA2 has been associated with coronary heart disease and vascular events.[3] However, the association between these biomarkers and long-term functional trajectories is unclear, and these biomarkers may allow the prognostication not only of vascular events but also of functional trajectories, as we have found in previous research.[4]. This evidence concerns the gene PLA2G7 and coronary artery disorder.