PLA2G7 and ischemic stroke: In a prior NOMAS analysis among 467 individuals with first ischemic stroke, LpPLA2 was independently associated with recurrent stroke (HR 2.08, 95% CI 1.04–4.18) and the composite outcome of recurrent stroke, MI, or vascular death.[25] In another NOMAS analysis of 1946 stroke-free participants,[26] LpPLA2 mass levels were associated with incident large-artery ischemic stroke among non-Hispanic Whites.