PHF5A and neoplasm: Furthermore, using IHC in our own NSCLC tissue microarrays, we validated that the protein level of PHF5A was also significantly upregulated in both LUAD and LUSC tumor tissues compared with paired nontumor tissues, and the high expression of PHF5A protein was significantly correlated with poor survival in LUAD patients but not LUSC patients, which was consistent with the findings obtained using TCGA data sets.