In addition, IRF7 is also involved in angiogenesis since Jin et al also showed that IRF7 over‐expression increased tumour formation with increased angiogenesis and cell heterogeneity by inducing inflammatory cytokine expression (IL6, CCL2 and CXCL1).29 This latter is in line with our results where we show an attenuated inflammatory response in absence of IRF7. This evidence concerns the gene CXCL1 and neoplasm.