For instance, circular RNA_LARP4 suppresses cell growth and migration in gastric cancer through modulating LATS1 expression via sponging miR-424 – 5p41; downregulation of miR-31 can stimulate the expression of LATS2 through modulating Hippo pathway, thus regulating epithelial-mesenchymal transition in ESCC42. Here, LATS1 is linked to gastric cancer.