NRG1 and Charcot-Marie-Tooth disease type 1A: We previously demonstrated that the treatment of CMT1A rats with recombinant NRG1, when restricted to early postnatal development, improves the CMT1A disease phenotype16, in line with our present findings on the stimulatory role of Schwann cell-derived NRG1-I in CMT1A, during early postnatal stages.