PXK and amyotrophic lateral sclerosis: The generalized linear regression model showed that of the nine SNPs associated with telomere length, two were also associated with ALS: rs8105767 near the ZNF208 gene (p = 1.29 × 10−4, MAF = 0.03) and rs6772228, which is in an intron for the PXK gene (p = 0.001, MAF = 0.03; Table 3), but the SKAT test did not show an association of overall variant burden in these genes with ALS after correction for multiple testing (ZNF208, p = 0.81 and PXK, p = 0.03).