In conclusion, the current meta-analysis indicates that the MMP-9 −1562 C > T, rs3918242 and Gln279Arg, rs17576 polymorphisms are not the independent risk factor for asthma susceptibility; however, the Arg668Gln, rs17577 polymorphism is the risk factor for asthma susceptibility. The gene discussed is MMP9; the disease is asthma.