While there is no clear evidence in human data sets of a role for FGF10 and/or FGF10 signaling in cystic fibrosis, studies in pig models showed that FGF10 treatment induced fluid secretion in non-CF fetal lung explants but was unable to do so in CF fetal lung explants (Meyerholz et al., 2018), suggesting that FGF10 signaling may play an important role in the pathogenesis of the disease. This evidence concerns the gene FGF10 and cystic fibrosis.