TNF and myeloid sarcoma: ANCOVA showed that MS was associated with greater IP-10 [F(2, 123) = 14.537, p < 0.001], TNF-α [F = 19.321, p < 0.001], IL-10 [F = 18.921, p < 0.001], and IL-8 [F = 23.358, p < 0.001] levels (Figure 2), but only IP-10 and IL-8 increased with age in MS (p < 0.001 for both).