Some studies revealed that γδT cells might inhibit fibrogenesis by inducing apoptosis of activated HSCs in a FasL-dependent manner, while others emphasized the pathogenic role of γδT cells through IL-17A-mediated enhancement of HSCs activation in CCl4-induced liver injury and liver fibrosis (8, 19, 30). The gene discussed is FASLG; the disease is Hepatic fibrosis.