DNAJC5 and infection: RTS,S is a self-assembling virus-like particle consisting of a recombinant protein containing part of the central tandem repeat from the P. falciparum circumsporozoite protein (CSP) plus epitopes from the CSP carboxy-terminal, targeting the sporozoite, and liver stages of infection, and fused to the S surface antigen of hepatitis B (HBsAg) virus and coexpressed with HBsAg alone.