ICAM1 and Alzheimer disease: Brain endothelial cells in AD express high level of inflammatory adhesion molecules, for instance cationic antimicrobial protein 37 kDa, MCP-1 and intercellular adhesion molecule-1 (ICAM-1; Frohman et al., 1991; Pereira et al., 1996; Grammas and Ovase, 2001).