MYC and acute lymphoblastic leukemia: Various oncogenes, such as TAL1, LMO2, HOXA, and c-Myc, participate in the development of ALL.However, c-Myc, which is downstream of the Notch-1signaling pathway, plays an important role in promotingcell growth and in the proliferation of malignant cells(Kamdje and Krampera, 2011; Gu et al., 2016).