2014; Cai et al. 2017; Hong et al. 2017). The HepG2 cell line, which is established from human hepatic carcinoma, is a suitable in vitro model and has been widely used to study the regulation of P-gp expression and function by xenobiotic drugs (Rigalli et al. 2011; He et al. 2014). Using the MTT assay, we confirmed that the treatment of BJJS at 0–160 μM for 24–72 h did not elicit remarkable cytotoxicity toward HepG2 cells (Figure 1(B)). This evidence concerns the gene PGP and hepatocellular carcinoma.