CD163 and colorectal carcinoma: Further prognostic analysis revealed that, at the invasive front of CRC, high level of CD68 expression was insignificantly associated with worse RFS (P = 0.095) (Fig. 1G) and OS (P = 0.229) (Fig. 1H), however, high level of CD163 expression was significantly correlated with poor RFS (P = 0.001) (Fig. 1I) and OS (P < 0.001) (Fig. 1J).