Another interesting finding originates from Hall et al. 2018 [35] showing evidence for PFD inhibiting TGF-β1-induced type I- and type III- collagens and targeting the p38 MAPK signaling pathway in human dermal fibroblasts which shows the capability of PFD to target dermal fibrosis. This evidence concerns the gene TGFB1 and polyostotic fibrous dysplasia.