After 6 weeks, the peritoneal surface tumor burden was significantly higher (P < 0.05) in mice that had received SKOV3/shCHIP‐1 cells (2.09 ± 0.33 g) vs. control cells (1.01 ± 0.22 g), whereas Snail knockdown suppressed the effect of CHIP knockdown (1.08 ± 0.24 g; Fig. 5A,B). The gene discussed is SNAI1; the disease is neoplasm.