HGF and cancer: Although MACC1 and S100A4 are involved in different biological pathways, that is, MACC1 as a key regulator of HGF‐MET signaling (Stein et al., 2009a) and S100A4 as a transcriptional target of β‐catenin/T‐cell factor signaling (Stein et al., 2006), our data suggest that MACC1 and S100A4 might be co‐regulated in cancer.