WAGR syndrome is a contiguous gene deletion syndrome on chromosome 11p13 characterized by Wilms’ tumour, Aniridia, Genitourinary anomalies and Mental retardation, with obesity present in patients with larger deletions encompassing BDNF along with the other critical genes (WAGRO syndrome) [10]. Here, BDNF is linked to Wilms tumor, aniridia, genitourinary anomalies, intellectual disability, and obesity syndrome.